Published on
Nov 4, 2026
On-virion structural dynamics reveal temperature- and receptor-coordinated activation of an alphacoronavirus spike
INTRODUCTION Throughout the last century, human coronaviruses (HCoVs) were primarily associated with mild symptoms of common cold, exemplified by low-pathogenic strains such as HCoV-229E and HCoV-OC43 (1, 2). This perception changed markedly following the …
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